QFT-Plus

Detail INfo

Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis complex organisms, including M. tuberculosis, M. bovis, and M. africanum. Transmission typically occurs when airborne droplets from an individual with active pulmonary TB infect a new host. The time from infection to disease onset can vary from a few weeks to several months, though most infected individuals maintain a stable condition. Latent tuberculosis infection (LTBI) is a non-contagious, asymptomatic state where TB bacteria remain dormant, sometimes for months or years, before potentially causing disease. The primary aim of diagnosing LTBI is to enable preventive medical intervention for TB
Two methods currently exist for diagnosing LTBI: the Tuberculin Skin Test (TST) and the Interferon-Gamma Release Assay (IGRA), which the later measures interferon-gamma levels in blood. The TST result is often influenced by the BCG vaccine and other non-TB mycobacteria, which may reduce its accuracy. The IGRA, however, is a newer TB infection diagnostic tool with high specificity and sensitivity and is unaffected by the BCG vaccine or most non-TB mycobacteria. The U.S. CDC includes IGRA in its TB diagnostic guidelines. QuantiFERON® is an IGRA-based test offering these diagnostic advantages
For more details on the 4th-generation "QuantiFERON®-TB Gold Plus (QFT-Plus)," please visit the manufacturer's (Qiagen) official website.

File name

last updated

Download

2025/01/21